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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b430650102207c8e7f4f46b87c1e33f081afc79dcccc0d1ab514054a8970c85' 
  AND token = 'D6jfYUHdRILvrS2KrSvtGUvbLvldc8f8oZtrwZ+dBP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}