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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4b6a58dbd3fbdcfd9d80b218642fb34b0a8d494b542d434bbe529ee9e9c822' 
  AND token = 'sW9b4olTUlUeTt5QLZWrLb2y7R8tdy7WzPlrMpUR8xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}