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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d21d68eb97c9b07527bb25e1332f7a7009108e369c3ceacfd66d18b61396dd9' 
  AND token = 'mr8Lun3sBT+ohwF3bFphw5a+N5waOD8q2gNcFhbtvJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}