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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a16e28ff629f88ac1b3b0a5c08790457bcb522830b476081e8d0d09283a772' 
  AND token = 'tyvrYCLp1IgiOf/BET8D0stkbWFnLeT4zUHe3Xl9FVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}