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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b53b1e39a25da06f3cd3931ba2184c6a6d48f67d09052b1aa5a3238d30522f' 
  AND token = '273pqaQfcrycfpTUnFT5PBwvdZU1sSwVc1ZmG9UTjTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}