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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001458bbb34993c296a7e47d225247651a72ac3b30ae4f80a478936c95885c59' 
  AND token = 'eK4/iZoQtU+goT0JE/5DNxVhpH43P9hnYbX2k35HZ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}