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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb6d07bdc99957a8edf101a8bff4eb9b0042a2294aa0e39e99595c12c9f5b356' 
  AND token = '8BM8AgpTAMjcxmFlGGNV6TUE04Pfiqn5rIlg+EHBDk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}