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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258a9fad83ff2f606f69e00144c5c9df68d525673ae5da3481e3703083e35adb' 
  AND token = 's79QsW2VYRaAC5uKSsBqwlx3tr+vy2geQ0PpKiAEPTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}