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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c0b39eefdd88b29c1fa10718d934a45416d65bb1a6c6c2e51f226c2fb094e9' 
  AND token = 'lXo8b4IVAnm7gnAP5S+ZKmpEQwob41z6uxgOZRkPvIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}