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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb2074a38e7b6d23535b23a76eb3a8c58a70a28bc221e358f015ab2d1c28a52a' 
  AND token = 'fqL3S6IDPsgQSpPCVm3pWBoUp2+hsMPGIbCmfd7G6AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}