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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157f423f11526b3c52cc0efd7756b002e4ae16c55f641ad2bfc7498cd5d0dca7' 
  AND token = '5vGfigErt0tNjKhGftk3jLxbTf63h8dJhaVpn+bztBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}