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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3de217f68e4f87c82c8afbe820cbc5fd42c1959374f1d890ae197e046dbd824' 
  AND token = 'wRoH0L1zi7EpM86L2CdRV7Q+c7DF3vY+wS9QUFV2rok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}