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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c1a43fb6027c67889d3ddf74d316a7d623edce31ae8db447743cea55a3cd98' 
  AND token = 'sYREDfjc+wtrroRf3qmtxbY0ppoqSDDq8xjMkj9yeZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}