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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3794dcb6f2514a279ba4ca90e7981878c0ad5d4bcc0e4e60d3fa7ca1b7ecc0' 
  AND token = 'TkFX2oWpH4XO8a/45dTyxwygyHdOgHRRp5mAA/NBZaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}