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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab26c50026f71503214b37c8100f5d41df5a4057ccbd79d1cae6f91b51f4cd3e' 
  AND token = 'U5yy8FbEJf9vPR5hqXFakNdnyU4ca4fM2xbtnqo/J04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}