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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff463b08f57b08e074cff8a86d851b99581dc40c07a30c49bd45d67aa9673ba0' 
  AND token = 'C3OT/HxCMy3YPgq1Zjbjk0FlCLukzZk3FxVJuCcRrDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}