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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14349b51402c856fb39a6563a65083f3daab587ace9ab282df678611eab54e4' 
  AND token = 'm+a0qFSE86lXMXk+ZlDY4pT2i8Rp3QKf4vkInDYqzFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}