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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c53644ca1f830048272ab0928cc6e19f712ffc9b41e94897cb738853753957e' 
  AND token = 'aFDtwO2CZ+6yH1kmfV5PL+36Uq++t9z/i6eHnzK8ITU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}