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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3776437f666239e044ee97e9127e053f4a5acb6b97680cdef0ff5f5f3320719' 
  AND token = '+SK/HneI41xh6sLLNU2cTAQMXIt1dOLE3FG0pZ71cAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}