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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e33123c1b2bdf2aaa7e1f9ebbbaff8a16f6ccc70878582e307b8ed2d5bc7ad4' 
  AND token = 'sJR37tROXl8AZwqd/BaVxKpRJLJ95FO8zvHwjL11pok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}