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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e643e7464285327997f6f42d686b931bd0836eb5f56daf53f485ec07ee86eed9' 
  AND token = 'MB4O3S0i8Tm6NIm0NoPaINhEvQHuoC7B6sf4fYMPdVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}