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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bdb9fd2ee7ac9c49611f992af666095e7f5b7f10df349a9965d2a588551b9e' 
  AND token = 'ROScq4Ha4aMdrnfA5FJX/jnM66UtIJiZcgJuiOQ+9ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}