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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0cea8c85b2ff4b262e394a8e623e4897784d5e0cc37a05a9f87e9443da12f1' 
  AND token = 'khm9CoxsS4L6sgSONmRobqc+kJ2AM0jNHZgMcBPucLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}