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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d74c23a778fd6225fa093ec42d69f5944b235dbc03182e982413ca9873c7bd9' 
  AND token = 'PPF32+9IgdwezmsUFdcD3TQZ8QMP+ueydBF4K8KEKuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}