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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce3b3d5d790e138154774c37d914bf1a3a0d0407408af144567d2e21e58b6d0' 
  AND token = 'JjHAMScX443m3wTauf7d+c8OYfHBLdUMCC+f5UmdQ0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}