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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f8bc88fb352e8fec736d794da080073df3836280003ab7a81b382fed57a03e' 
  AND token = 'nxWSJYyyFx//LQQLRYbSj/SgQMMfQIGJQyM5MzrOXG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}