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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a771b137192224c3a46f49dfae74fc7e5bff75013a9a168c96fb8fdf124e51' 
  AND token = 'e4O09bW8fxhapTD1jxl5zaTfHa3KtJR7/kOA5an07Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}