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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fddf5805d5c818662a280fe368e8dabea5b24cca0e73e0a80e582fd8f81cc9c' 
  AND token = 'hD0mTUlUs+RfLntYuqRh1jZy5R92WdKc5o3GwGstGb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}