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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeb8257317f455d6a082418ad2ba34ccddb117a460de6ca9b446d1c220f38426' 
  AND token = '1Z40sMqvBiEm6Yts8i/WWyW2T4NGlb7WsszZJwhaUHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}