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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78203b059c64ccdef6eb897e13c5a30983f050c8c937831e04591395b674be3a' 
  AND token = 'ROaPv7avhBv5Wco2KzAYu74ZNm9r3lLzyUv5KPbW/L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}