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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2f5efd355ccc73a4e67cfef92f3fe5d88c7283947d51f5bffee462fae20548' 
  AND token = 'eYBEN5Hq2vbz0R8C+dwxlZ3s47N1xT29CjS3WO/+K6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}