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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4350a684f9c1479fcf83f6d1702a4207738edbe0ae2f8758559517f746ed5e89' 
  AND token = 'ho/1NIxKEHklFSme+tjN1+cx8xx/4nKgxXF35YtKJ18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}