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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0312b1fefb74fd32fda853d4fee619cfb0e42de54c09f4ff15af3fc575e86b' 
  AND token = 'G1PlyIpHiY0D8GQem3mwlRkCho0EHXFsYLDa+TlOQdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}