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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bfdcc9d1cc6585d09091e3a66f54ab9ccf25077a5e08c89ca17a1d10deaf207' 
  AND token = 'C2G6EiQhGkTf965/xMZlXhLFjeyXAj2E9SPBBXxRyJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}