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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8b395648e2b9d496b105c4ebb8a9eb4a7346e1824199254267495e31ef3a7b' 
  AND token = 'UoED5RSuu1q0NQbQCzVHQjouI6VVhm3TEbD3QiUWPMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}