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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74df297ed19e4c676e7943f395fa4c901d2099d2b53b1789e8bdec1d5fcb8437' 
  AND token = 'I1WCFYQZILgL8mtwjpsalf2pcbu4+PlpM+HROf2mtA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}