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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb3370a4d09dbd8ece86a9c04e018684fb8cf048d7f3378e60b77fa2bdc6123' 
  AND token = 'PPEUXcr8GAZMTfqADh8q6rkGa7ThJCaDfAmD2CEJwbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}