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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1806f20d7762ba0a97296689d5f325e00ec43a3d29bf05b231560c822c4f4fb' 
  AND token = 'm5HRyfLry/H8a+DGv6vpzLy89iZ1iJAk31uiwLWcD/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}