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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '283dc9075cbe4ee8dfebae497986142a485a94b1b8bf6fdf8b953d244a852dd7' 
  AND token = 'E2XmEdC775kAEtEPTl6IIDI5yGmwYHKOa7Ybs6CUoJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}