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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0666b5e65362050256533e23d02a1fb721f94ea682c086acc17cb5ccf22e983' 
  AND token = '59Q0jIR6mb3Vfm+9uzq6ptItSp+bZoNQcyJ/VxJVD7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}