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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9d1e3902b6bdb688617661dee3514d53a77a97e42f9fcafcb958f53560e2df' 
  AND token = 'hdxjeSwE8cYDp4W7fogKAIcaCYIEkTkIT4y5F4uEp9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}