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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3a1be66866cfa753d3594acca718bdd8ccc240988d807b6039ea104e93a8a2' 
  AND token = '1KUJ9PjF1jeFZ34ZS0PPl04Ewmtq1kqRVgG8S8hLMm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}