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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be143c5dde2c103e471a7cf04128c5f0593d6062bd13d757c724963f569712b5' 
  AND token = 'j9FLPNHnbs9KDN+tsSSHJdMgjO8DRvL4B6Elw8FrrrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}