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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c7ffe7b23e56acbe6c595b5037cdf2128f0b0d53e43fd89cd703e86d4cf979' 
  AND token = 'PCPLQ2HGeAPqQru/94NamuNEvcEfwvPtpAAfVw2SMrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}