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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440c688bb916ca266bfa8130c4098d7d8946b8f77f759b2e6d3b5fda66b7e6b3' 
  AND token = 'AfWhDOfTfMYzWXNi8wOoFAt2uVEJA9k1BSLisRyQ6jY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}