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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0498406588357437da28192a16b9bbe74a6eb7feb1e2d01285706f46aca6e3' 
  AND token = 'kiISVTurAQrYUEuZr3azDHfs9cguZ6oHtwTqs+Vo5QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}