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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7623c5c657b565cee767ea033c359c12afc5645fa598c93571e7858826eafb' 
  AND token = 'i9ZdvEWtaYEGxmc+TwLSxrA1XNSeNmD3ogs4SgziQCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}