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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d643d2e944e0f29b409a9208a135a9fd31ef301a48e1cc4cf28f3569581e56' 
  AND token = 'j3WY+wudJDi6CBxUQT/2F5llssmh9OSgQp0h0+22Rr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}