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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5d484fba147bfe4e08e7a9d7de1ffec0c3c197c39034ddd06e83e8ce90e441' 
  AND token = 'qMyOTFKib6EklZg81NigtGlXDdgN4CBq7S5GppjhxjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}