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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8cffcdf86216fa2e61ce0207357cb374968d8e84e9287c03ef109a19191a80f' 
  AND token = '5CndFMOGdMaEYVtkB95Oh1Hp+TMikSiMCSqv9NLgtoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}